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Author: Shailendra K. Saxena Publisher: BoD – Books on Demand ISBN: 9535122614 Category : Science Languages : en Pages : 203
Book Description
This book gives a comprehensive overview of recent advances in Retrovirology, as well as general concepts of molecular biology of retroviral infections, immunopathology, diagnosis, and prevention, to current clinical recommendations in management of retroviruses, including endogenous retroviruses, highlighting the ongoing issues, recent advances, with future directions in diagnostic approaches and therapeutic strategies.
Author: Shailendra K. Saxena Publisher: BoD – Books on Demand ISBN: 9535122614 Category : Science Languages : en Pages : 203
Book Description
This book gives a comprehensive overview of recent advances in Retrovirology, as well as general concepts of molecular biology of retroviral infections, immunopathology, diagnosis, and prevention, to current clinical recommendations in management of retroviruses, including endogenous retroviruses, highlighting the ongoing issues, recent advances, with future directions in diagnostic approaches and therapeutic strategies.
Author: Adeline Foley Publisher: American Medical Publishers ISBN: 9781639272631 Category : Medical Languages : en Pages : 240
Book Description
The study of viruses is known as virology. It involves the study of their sub-microscopic, parasitic particles and virus-like agents. It also focuses on their structure, classification and evolution, the ways in which they infect host cells the diseases they cause, and the ways to cure them. The study of retroviruses is known as retrovirology. A retrovirus is a kind of RNA virus. It inserts a copy of its genome in the host cell's DNA that occupies it thus changing the genome of that cell. Retroviruses are valuable research tools in molecular biology. These viruses are either single-stranded RNA or double-stranded DNA viruses. The main virion components in retroviruses are envelope, RNA, protein, etc. Retroviruses cause tumor growth and certain cancers in animals and in human beings, it causes diseases like AIDS. This book aims to shed light on some of the unexplored aspects of retrovirology and recent researches in this field. The various advancements in retrovirology are glanced at and their applications, as well as ramifications are looked at in detail. This book is a vital tool for all researching and studying this field.
Author: Shailendra K. Saxena Publisher: ISBN: 9789535146025 Category : Languages : en Pages : 202
Book Description
This book gives a comprehensive overview of recent advances in Retrovirology, as well as general concepts of molecular biology of retroviral infections, immunopathology, diagnosis, and prevention, to current clinical recommendations in management of retroviruses, including endogenous retroviruses, highlighting the ongoing issues, recent advances, with future directions in diagnostic approaches and therapeutic strategies.
Author: Anna Marie Skalka Publisher: Harvard University Press ISBN: 0674988752 Category : Science Languages : en Pages : 193
Book Description
Approximately eight percent of our DNA contains retroviral sequences that are millions of years old. Through engaging stories of scientific discovery, Anna Marie Skalka explains our evolving knowledge of these ancient denizens of the biosphere and how this understanding has significantly advanced research in genetic engineering, gene delivery systems, and precision medicine. Discovering Retroviruses begins with the pioneer scientists who first encountered these RNA-containing viruses and solved the mystery of their reproduction. Like other viruses, retroviruses invade the cells of a host organism to reproduce. What makes them “retro” is a unique process of genetic information transfer. Instead of transcribing DNA into RNA as all living cells do, they transcribe their RNA into DNA. This viral DNA is then spliced into the host’s genome, where the cell’s synthetic machinery is co-opted to make new virus particles. The 100,000 pieces of retroviral DNA in the human genome are remnants from multiple invasions of our ancestors’ “germline” cells—the cells that allow a host organism to reproduce. Most of these bits of retroviral DNA are degenerated fossils, but some have been exploited during evolution, with profound effects on our physiology. Some present-day circulating retroviruses cause cancers in humans and other animals. Others, like HIV, cause severe immunodeficiencies. But retroviruses also hold clues to innovative approaches that can prevent and treat these diseases. In laboratories around the world, retroviruses continue to shed light on future possibilities that are anything but “retro.”
Author: Reinhard Kurth Publisher: Caister Academic Press Limited ISBN: 9781904455554 Category : Science Languages : en Pages : 0
Book Description
Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
Author: John M. Coffin Publisher: CSHL Press ISBN: 9780879695712 Category : Electronic books Languages : en Pages : 856
Book Description
For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Author: Hans-Georg Kräusslich Publisher: Springer ISBN: 9783642801471 Category : Medical Languages : en Pages : 0
Book Description
Retroviruses arguably belong to the most fascinating of all viruses because of their unusual and highly efficient mode of replication involving reverse transcription and integration of the viral genome and a complex system of transcriptional and post transcriptional regulatory mechanisms. The importance of ret roviruses as human and animal pathogens has also enhanced scientific and medical interest in this diverse group of viruses and has spurred an intensive search for novel and improved antiviral agents. More recently, analysis of retroviral replication and in particular understanding the formation and composition of the virus particle has received additional attention because of the promise of retroviral vectors as vehicles for human somatic gene therapy. Many recent advances have been made in our understanding of the molecular mechanisms governing as sembly and release of infectious retrovirus particles. This book attempts to summarize these recent developments and to provide an overview of our current knowledge on retrovirus particle formation. The individual chapters of the book deal with specific steps in the pathway of retroviral morphogenesis and maturation, starting at the time when the components of the virus have been synthesized within the infected cell and ending once the infectious virion has been released from the cell. An introductory chapter provides a comparative description of the structure and morphology of various retroviruses.
Author: Adeline Foley Publisher: American Medical Publishers ISBN: 9781639272617 Category : Medical Languages : en Pages : 235
Book Description
Retrovirology is the study of retroviruses. A retrovirus is a kind of RNA virus that inserts a copy of its genome into the DNA of a host cell, thus changing the genome of that cell. These viruses are either single-stranded RNA or double-stranded DNA viruses. The main viron components found in retroviruses are envelope, RNA and protein. Both animals and humans are affected by retroviruses. It causes tumor growth and certain cancers that are linked with slow infections of animals such as equine infectious anemia. Retroviruses such as HTLV-1 cause cancer called adult T-cell leukemia in human beings. Other retroviruses such as HIV cause AIDS in human beings. The treatment of diseases by retrovirus can be done with the help of antiretroviral drugs and medications. This book unravels the recent studies in the field of retrovirology. It traces the progress of this field and highlights some of its key concepts and applications. It is a vital tool for all researching or studying retrovirology, as it gives incredible insights into emerging trends and concepts.
Author: Adeline Foley Publisher: ISBN: 9781632417961 Category : Languages : en Pages : 249
Book Description
The type of RNA virus, which inserts a copy of its genome into the DNA of a host cell that it invades, and changes the genome of that cell, is known as a retrovirus. Such type of viruses are classified as single-stranded positive-sense RNA viruses. The study of retroviruses is called retrovirology. On entering the host cell's cytoplasm, the retroviruses use their own reverse transcriptase enzyme to produce DNA from their RNA genome, which is the reverse or retro of the usual pattern. Then the new DNA incorporates into the host cell genome with the help of an integrase enzyme. Some retroviruses such as Rous sarcoma virus and mouse mammary tumor virus can trigger tumor growth. Some others can cause infections like HIV. This book aims to shed light on some of the unexplored aspects of retrovirology and the recent researches in this field. It traces the progress of this field and highlights some of its key concepts and applications. It will help the readers in keeping pace with the rapid changes in this field.
Author: Shailendra K. Saxena
Author: Shailendra K. Saxena
Author: Adeline Foley
Author: Shailendra K. Saxena
Author: Reinhard Kurth
Author: Anna Marie Skalka
Author: Reinhard Kurth
Author: John M. Coffin
Author: Hans-Georg Kräusslich
Author: Adeline Foley
Author: Adeline Foley