Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Advances in Molecular Cytogenetics PDF full book. Access full book title Advances in Molecular Cytogenetics by Clayton Fisher. Download full books in PDF and EPUB format.
Author: Clayton Fisher Publisher: Foster Academics ISBN: 9781632426970 Category : Medical Languages : en Pages : 255
Book Description
The field of molecular cytogenetics is concerned with the combination of the fields of cytogenetics and molecular biology, to distinguish normal cells from cancer-causing cells. It is a useful tool for the diagnosis and treatment of malignancies of the brain, blood, etc. Novel techniques known as fluorescence in situ hybridization (FISH) are used for molecular cytogenetic studies. These have DNA labeled with uniquely colored fluorescent tags to image specific regions of the genome. Molecular cytogenetic techniques are crucial for the understanding of the structural and functional organization of the nucleus and the chromosome, genome variation, gene expression and evolution. These also give insight into the contribution of genomic variations and chromosomal abnormalities to tumor genetics and medical genetics. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of molecular cytogenetics. It is an upcoming field of science that has undergone rapid development over the past few decades. Students, researchers, experts and all associated with this field will benefit alike from this book.
Author: Clayton Fisher Publisher: Foster Academics ISBN: 9781632426970 Category : Medical Languages : en Pages : 255
Book Description
The field of molecular cytogenetics is concerned with the combination of the fields of cytogenetics and molecular biology, to distinguish normal cells from cancer-causing cells. It is a useful tool for the diagnosis and treatment of malignancies of the brain, blood, etc. Novel techniques known as fluorescence in situ hybridization (FISH) are used for molecular cytogenetic studies. These have DNA labeled with uniquely colored fluorescent tags to image specific regions of the genome. Molecular cytogenetic techniques are crucial for the understanding of the structural and functional organization of the nucleus and the chromosome, genome variation, gene expression and evolution. These also give insight into the contribution of genomic variations and chromosomal abnormalities to tumor genetics and medical genetics. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of molecular cytogenetics. It is an upcoming field of science that has undergone rapid development over the past few decades. Students, researchers, experts and all associated with this field will benefit alike from this book.
Author: James Arthur Birchler Publisher: ISBN: 9783805594943 Category : Plant cytogenetics Languages : en Pages : 0
Book Description
The research reported in this volume illustrates the utility of incorporating cytogenetic tools into biological studies. Somatic chromosome identification is now becoming routine in selected plant species, and the utility of this technique will increase as it expands to other taxa. Individual genes or DNA fragments can be localized to chromosomes in combination with chromosomal identification techniques, which bypasses the need for multiple generations of genetic analysis to map molecular markers to chromosomal positions. The identity of individuals with chromosomal changes can be determined in root tip metaphase spreads, with subsequent growth of these individuals for further genetic and molecular analyses. These new techniques have allowed examination of chromosomal behavior in meiotic and somatic preparations at the whole-genome level. They are also the basis for studies of changes in chromosomal structure or transposable elements in different cells of a single tissue. The studies in this volume illustrate many of these applications and the diversity of research avenues they open up. This publication will be of interest to cytogeneticists, cytologists, cell biologists and evolutionary biologists.
Author: Marcelo L. Larramendy Publisher: BoD – Books on Demand ISBN: 1839689412 Category : Medical Languages : en Pages : 170
Book Description
This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.
Author: Camila Blair Publisher: American Medical Publishers ISBN: 9781639272464 Category : Medical Languages : en Pages : 233
Book Description
Molecular cytogenetics is a combination of molecular biology and cytogenetics. Molecular biology is a subset of biology that is concerned with the molecular basis of biological activity which occurs between biomolecules in numerous systems of a cell. Cytogenetics, on the other hand, is a field of genetics that deals with how the chromosomes are related to cell behavior during mitosis and meiosis. The aim of molecular cytogenetics is to distinguish between normal and cancer-causing cells using various substances. It is a useful tool for diagnosis and treatment of various malignancies like haematological malignancies, brain tumors, etc. It uses the techniques of fluorescent in situ hybridization and comparative genomic hybridization. This book unravels the recent studies in the field of molecular cytogenetics. It strives to provide a fair idea about this discipline and to help develop a better understanding of the latest advances within this field. Students, researchers, experts and all associated with molecular cytogenetics will benefit alike from this book.
Author: Sverre Heim Publisher: John Wiley & Sons ISBN: 1118795512 Category : Medical Languages : en Pages : 648
Book Description
The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
Author: Marcelo B. Cioffi Publisher: S. Karger AG (Switzerland) ISBN: 9783318025286 Category : Fishes Languages : en Pages : 0
Book Description
Fish exhibit the greatest diversity of all vertebrates, making this group extremely attractive for the study of a number of evolutionary questions. Besides, fish genomes have intrinsic characteristics that may be responsible for this amazing diversity, but little is known about their structure and organization. Major advances in chromosomal studies were achieved in the current 'molecular cytogenetic era' based on detecting DNA sequences on chromosomes, parts of chromosomes or even whole genomic DNA by fluorescence in situ hybridization. In this issue, a collection of review articles is presented together with current research results, demonstrating the advances made using this specific methodology in fish research. The contributions provide a timely update on recent developments in fish molecular cytogenetics, covering topics such as karyotype evolution, sex and B chromosomes, polyploids, and molecular evolution. Researchers, teachers, and students interested in the structural features and evolutionary dynamics of fish genomes will find this publication a valuable source of current knowledge.
Author: Sverre Heim Publisher: John Wiley & Sons ISBN: 1118210581 Category : Medical Languages : en Pages : 799
Book Description
Cancer Cytogenetics, 3rd Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area and incorporates a vast amount of new data from the latest basic and clinical investigations. Edited by two leading experts, and now involving a new panel of international experts, the book offers an authoritative description of neoplastic processes at the chromosomal level of genomic organization. Researchers in cytogenetics, medical and molecular genetics, cellular and molecular biology, cancer research, clinical oncology, and hematology will find this reference both thorough and authoritative.
Author: Hank Bass Publisher: Springer Science & Business Media ISBN: 0387708693 Category : Science Languages : en Pages : 346
Book Description
This reference book provides information on plant cytogenetics for students, instructors, and researchers. Topics covered by international experts include classical cytogenetics of plant genomes; plant chromosome structure; functional, molecular cytology; and genome dynamics. In addition, chapters are included on several methods in plant cytogenetics, informatics, and even laboratory exercises for aspiring or practiced instructors. The book provides a unique combination of historical and modern subject matter, revealing the central role of plant cytogenetics in plant genetics and genomics as currently practiced. This breadth of coverage, together with the inclusion of methods and instruction, is intended to convey a deep and useful appreciation for plant cytogenetics. We hope it will inform and inspire students, researchers, and teachers to continue to employ plant cytogenetics to address fundamental questions about the cytology of plant chromosomes and genomes for years to come. Hank W. Bass is a Professor in the Department of Biological Science at Florida State University. James A. Birchler is a Professor in the Division of Biological Sciences at the University of Missouri.
Author: Thomas Liehr Publisher: Academic Press ISBN: 0128235802 Category : Science Languages : en Pages : 430
Book Description
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book’s second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease Features chapter contributions from international leaders in the field
Author: Publisher: Academic Press ISBN: 9780123854940 Category : Science Languages : en Pages : 400
Book Description
Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays Discusses many new assays developed since the previous edition Presents recent developments in cytometric intrumentation/technology
Author: Clayton Fisher
Author: Clayton Fisher
Author: James Arthur Birchler
Author: Marcelo L. Larramendy
Author: Camila Blair
Author: Sverre Heim
Author: Marcelo B. Cioffi
Author: Sverre Heim
Author: Hank Bass
Author: Thomas Liehr
Author: