Advances in Molecular and Cellular Endocrinology PDF Download

Author: D. LeRoith
Publisher: Elsevier
ISBN: 0080526381
Category : Medical
Languages : en
Pages : 289

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Book Description
Historically the field of endocrine research has always been at the forefront of scientific endeavors. The investigators of these important breakthroughs in research have been rewarded by numerous Nobel awards. In the field of diabetes alone, Nobel prizes have been awarded to researchers who discovered insulin, characterized the protein and invented radioimmunoassays using insulin as a paradigm. Not surprisingly, biomedical researchers have always been attracted by the endocrine system and other similar systems of intercellular communication.Over the past two decades, endocrine research has developed rapidly and adapted modern molecular and cellular biology techniques for its specific use. These changes have allowed researchers in the field to maintain their edge. Thus, endocrine disease-related genes have been characterized and mutations in these genes have helped explain common and less common endocrine disorders. Our understanding of the regulation of gene expression has been greatly enhanced by molecular techniques. In an attempt to bring investigators up to date with the recent advances in this exploding field we have decided to publish a series entitled Advances in Molecular and Cellular Endocrinology. Internationally famous investigators have agreed to participate and their contributions are appreciated. Volume 1 has focused on aspects of the hypothalamic-pituitary axis including GnRH and GH gene regulation, molecular aspects of insulin, insulin-like growth factors and glucagon. In addition, reviews on the recently cloned calcium receptor and steroid receptor interactions with DNA are presented.

Author: Ricardo V. Lloyd
Publisher: Springer Science & Business Media
ISBN: 1441910697
Category : Medical
Languages : en
Pages : 602

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Book Description
Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition provides detailed coverage of endocrine pathology with extensive discussion of the differential diagnosis as well as presentation of molecular pathobiology of the major endocrine organs. Revised and expanded from the first edition, each chapter, written by leaders in their respective field, has been updated with the latest advances that are transforming the field of endocrine pathology. Richly illustrated with color photomicrographs, useful diagrams and line drawings, each chapter includes differential diagnosis of common and uncommon lesions as well as material on molecular developments, with emphasis on the molecular findings that are most helpful in the diagnosis of specific disorders. Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition, provides a useful and well-organized resource designed not only for the endocrine pathologist and the general surgical pathologist, but also for the clinical endocrinologist and the endocrine surgeon.

Author: Saber Saleuddin
Publisher: CRC Press
ISBN: 1000047482
Category : History
Languages : en
Pages : 420

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Book Description
Advances in Invertebrate (Neuro)Endocrinology: A Collection of Reviews in the Post-Genomic Era (2-volume set) provides an informative series of reviews from expert scientists who are at the forefront of their research into the endocrinology of invertebrates. These two volumes are timely and appropriate in this post-genomic era because of the rapid pace of change brought about by genome projects, functional genomics, and genetics (omics technologies). The volume shows the rich history and strong tradition of cutting-edge research using invertebrates that has opened up our broader understanding of comparative endocrinology and the evolution of regulatory pathways and systems. These reviews set the scene and context for this exciting new era of understanding that has come from this post-genomic revolution. This book undertakes the daunting task of covering most of the diverse endocrine systems that exist among invertebrates. The papers in this book will advance our knowledge of invertebrate endocrinology but also of endocrinology in general, making the book will be valuable to researchers and students.

Author: Dhavendra Kumar
Publisher: Academic Press
ISBN: 0128094427
Category : Science
Languages : en
Pages : 607

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Book Description
Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Author: Bruce White
Publisher: Elsevier Health Sciences
ISBN: 032359574X
Category : Medical
Languages : en
Pages : 288

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Book Description
Gain a foundational understanding of how endocrine and metabolic physiology affects other body systems in health and disease, including the clinical dimensions of reproductive endocrinology. Endocrine and Reproductive Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book. - Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam. - Includes nearly 200 clear, 2-color diagrams that simplify complex concepts. - Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations. - Keeps you current with recent advances in endocrine physiology with expanded material on reproductive endocrinology and metabolism, and many updates at the molecular and cellular level. - Covers the latest developments in fertilization, pregnancy, and lactation, as well as fetal development, puberty, and the decline of reproductive function with age. Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs. - Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology - Johnson: Gastrointestinal Physiology - Koeppen & Stanton: Renal Physiology - Cloutier: Respiratory Physiology - Pappano & Weir: Cardiovascular Physiology - Hudnall: Hematology: A Pathophysiologic Approach

Author: S.S. Nussey
Publisher: CRC Press
ISBN: 9780203450437
Category : Medical
Languages : en
Pages : 382

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Book Description
Traditionally, endocrinology textbooks have been either short notes or multi-author, multi-volume monster, all of which present clinical material last and often only briefly. Endocrinology is different and used real cases to lead readers into the text and then describes the biochemistry, physiology, and anatomy they need to understand the case. The

Author: National Research Council
Publisher: National Academies
ISBN: 0309039274
Category : Science
Languages : en
Pages : 471

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Book Description
Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.

Author:
Publisher:
ISBN: 9780762301584
Category :
Languages : en
Pages : 270

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Book Description

Author: Lawrence I. Gilbert
Publisher: Academic Press
ISBN: 0123848512
Category : Science
Languages : en
Pages : 589

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Book Description
The publication of the extensive seven-volume work Comprehensive Molecular Insect Science provided a complete reference encompassing important developments and achievements in modern insect science. One of the most swiftly moving areas in entomological and comparative research is endocrinology, and this volume, Insect Endocrinology, is designed for those who desire a comprehensive yet concise work on important aspects of this topic. Because this area has moved quickly since the original publication, articles in this new volume are revised, highlighting developments in the related area since its original publication. Insect Endocrinology covers the mechanism of action of insect hormones during growth and metamorphosis as well as the role of insect hormones in reproduction, diapause and the regulation of metabolism. Contents include articles on the juvenile hormones, circadian organization of the endocrine system, ecdysteroid chemistry and biochemistry, as well as new chapters on insulin-like peptides and the peptide hormone Bursicon. This volume will be of great value to senior investigators, graduate students, post-doctoral fellows and advanced undergraduate research students. It can also be used as a reference for graduate courses and seminars on the topic. Chapters will also be valuable to the applied biologist or entomologist, providing the requisite understanding necessary for probing the more applied research areas. - Articles selected by the known and respected editor-in-chief of the original major reference work, Comprehensive Molecular Insect Science - Newly revised contributions bring together the latest research in the quickly moving field of insect endocrinology - Review of the literature of the past five years is now included, as well as full use of data arising from the application of molecular technologies wherever appropriate

Author: Boris Draznin
Publisher: Springer Science & Business Media
ISBN: 1461202418
Category : Medical
Languages : en
Pages : 411

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Book Description
In a rapidly evolving and extremely important area of medical science, it is often difficult for the student, teacher, and researcher to keep abreast of all the important advances. The purpose of Molecular Biology ofDiabetes, Parts I and II is to bring to these individuals the latest knowledge of diabetes-related research in a comprehensive, yet concise manner. To this end, we have assembled chapters, written by most of the world's experts in the field, that we believe compre hensively survey and synthesize a coherent understanding of the subject. Studies of the etiology of type I and type II diabetes are extremely exciting and essential, since we hope to one day prevent the disease using gene therapy. These aspects are covered in Molecular Biology of Diabetes: I. Autoimmunity and Genetics; Insulin Synthesis and Secretion. In type II diabetes, an abnormality in pancreatic secretion exists concomitantly with peripheral insulin resistance. This abnor mality of insulin secretion is believed to be related to a defect(s) in glucose sensing. Uncoupling of glucose sensing from insulin secre tion may be the crucial step in the pathogenesis of noninsulin-depen dent diabetes. In this volume, we have invited authors to describe their studies on all known factors affecting ~-cell function, including autoimmunity and genetics of diabetes, as well as molecular mecha nisms of insulin synthesis and secretion. In the last few years, the most rapidly advancing area of research in diabetes has been, in fact, related to insulin action.