Advances in Hepatic Encephalopathy and Urea Cycle Diseases PDF Download

Author: Gunter Kleinberger
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Amino acid metabolism
Languages : en
Pages : 792

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Author: Robert S. Brown Jr
Publisher: Elsevier Health Sciences
ISBN: 0323376045
Category : Medical
Languages : en
Pages : 161

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Book Description
Dr. Brown provides a timely upate on the clinical diagnosis and management of Hepatic Encephalopathy. His issue addresses current hot topics including Role of NH4 in Pathogenesis of Hepatic Encephalopathy; How to diagnose and manage HE in fulminant hepatic failure; New methods of Brain Imaging and testing (eg PET) and Hepatic Encephalopathy; Management New agents for HE (focus on NH4 lowering drugs used in UCD); Legal responsibility of MD when he diagnoses HE; Diets in Encephalopathy; and Neurological manifestations of HE.

Author: Vicente Felipo
Publisher: Springer Science & Business Media
ISBN: 1461559456
Category : Medical
Languages : en
Pages : 280

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Proceedings of an international symposiu, held in Valencia, Spain, December 2-4, 1996

Author: Santiago Grisolía
Publisher: Springer Science & Business Media
ISBN: 1461524849
Category : Medical
Languages : en
Pages : 150

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Book Description
This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye's syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues, including brain, is also presented, as well as the effects of hyperammonemia on brain metabolism and function and on brain microtubules. The control of cerebral protein breakdown is reviewed. The classical and some recently proposed clinical treatments as well as nutritional considerations in the management of patients with liver failure are also discussed.

Author:
Publisher:
ISBN: 9780947678111
Category : Ammonia
Languages : en
Pages : 524

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Author: Finn Bengtsson
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 600

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Author: Livio Capocaccia
Publisher: CRC-Press
ISBN: 9780849389641
Category : Medical
Languages : en
Pages : 672

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Book Description
This is a comprehensive reference covering the advances in hepatic encephalopathy (HE) and metabolic nitrogen exchange. Written by experts in their fields, the text discusses various aspects of hepatic nitrogen metabolism, protein metabolism, renal ammonia metabolism, neurobiology and neuropharmacology, and ammonia in the pathogenesis of HE. Benzodiazepine receptor ligands in the pathogenesis of HE are featured, and amino acids, amines, and zinc in the pathogeneis of HE are investigated. Studies done with various animal models are included. New techniques, MR spectroscopy and imaging, are highlighted. Steps for the diagnosis and assessment of HE are provided, and the effects of therapy are examined. Useful information is given regarding the metabolic aspects of liver cirrhosis and liver cell physiology.

Author: Vicente Felipo
Publisher: Springer
ISBN: 9781461358206
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume contains the papers presented at the International Symposium on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy", held in Valencia, Spain, January 24th-27th, 1994. Liver cirrhosis and other hepatic dysfunctions such as fulminant hepatic failure and congenital defects of urea cycle enzymes can lead to hepatic encephalopathy, coma and death. Hepatic encephalopathy is one of the main causes of death in western countries. The ability to detoxify ammonia by its incorporation into urea is diminished by impaired liver function, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. However, the molecular bases of the pathogenesis of hepatic encephalopathy and the role of hyperammonemia in this process remain unclear and several hypotheses have been proposed. To clarify the mechanisms involved in hepatic encephalopathy and hyperammonemia suitable animal models are necessary. The animal models available and the ideal features of an animal model are presented in the initial part of the book.

Author: Georgios Tsoulfas
Publisher: BoD – Books on Demand
ISBN: 1789850657
Category : Medical
Languages : en
Pages : 250

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Book Description
The goal of this book is to present a review of the different categories of liver disease, as well as address the role of surgery in managing these complex diseases. The book includes chapters written by international experts on the most current indications and guidelines regarding the diagnoses and management of liver diseases, as well as a variety of technical elements involved with the surgical procedures. Different surgical techniques involved in performing a hepatectomy will be discussed, including various instruments used, as well as the effect of modern technology as evidenced by novel procedures. An important focus of the book has been identifying the proper place of all these hepatectomy methods in the armamentarium of the experienced hepatobiliary surgeon, including the role of locoregional treatments such as ablation and embolization as adjuncts. Finally, the role of hepatectomy compared to orthotopic liver transplantation is discussed, so that the reader can have a well-rounded picture of the challenges and opportunities involved. Overall, this book has the potential to serve as an invaluable "tool" for both the hepatologist and the internist, as well as for the hepatic surgeon

Author: Peter B. Soeters
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 640

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