Advances in green synthesis for drug discovery PDF Download

Author: Florent Allais
Publisher: Frontiers Media SA
ISBN: 2832519342
Category : Science
Languages : en
Pages : 140

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Author: Marianna Torok
Publisher: Elsevier
ISBN: 0128232714
Category : Medical
Languages : en
Pages : 568

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Book Description
Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Author: Bimal Krishna Banik
Publisher: Elsevier
ISBN: 0443161674
Category : Science
Languages : en
Pages : 699

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Book Description
Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Author: Inamuddin
Publisher: Springer Nature
ISBN: 3030678849
Category : Science
Languages : en
Pages : 301

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Book Description
This edited book focusses on green chemistry as the research community endeavours to create eco-friendly materials and technologies. It provides an in-depth overview of the fundamentals, key concepts and experimental techniques for eco-friendly synthesis of organic compounds and metal/metal oxide nanoparticles/nanomaterials. It also emphasizes the mechanisms, designing and industrial technologies for green synthesis and its applications. Each chapter brings the recent developments, state of the art, challenges and perspectives which cover all the aspects in one place, and which concern the green synthesis and evolution. Authored by world-renowned experts in a broad range of green chemistry sectors, this book is an archival reference guide for researchers, engineers, scientists and postgraduates working in the field of sustainable science, green chemistry, environmental science, engineering sciences and industrial technologies.

Author: Paul F. Richardson
Publisher: Humana
ISBN: 9781071615775
Category : Medical
Languages : en
Pages : 595

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Book Description
This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores greener approaches to chemical transformations that are both prevalent and have been highlighted as challenging within the pharmaceutical industry, overall synthetic strategy, as well as the implementation and impact of a range of enabling technologies within medicinal chemistry. As a volume of the Methods in Pharmacology and Toxicology series, chapters provide the kind of key insight that can guide researchers toward greater success in the lab. Authoritative and practical, Green Chemistry in Drug Discovery: From Academia to Industry provides both a fundamental insight into the progress that has been made as well as some of the challenges that still exist for these techniques to be effectively implemented in the drug discovery process in a routine manner.

Author: Bimal Krishna Banik
Publisher: Elsevier
ISBN: 0443161658
Category : Science
Languages : en
Pages : 658

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Book Description
Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry 2e encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This first volume of the second edition covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources including plants and agricultural materials. Highlights the need for the adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these factors Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Author: Inamuddin
Publisher:
ISBN: 9783030678852
Category :
Languages : en
Pages : 0

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Book Description
This edited book focusses on green chemistry as the research community endeavours to create eco-friendly materials and technologies. It provides an in-depth overview of the fundamentals, key concepts and experimental techniques for eco-friendly synthesis of organic compounds and metal/metal oxide nanoparticles/nanomaterials. It also emphasizes the mechanisms, designing and industrial technologies for green synthesis and its applications. Each chapter brings the recent developments, state of the art, challenges and perspectives which cover all the aspects in one place, and which concern the green synthesis and evolution. Authored by world-renowned experts in a broad range of green chemistry sectors, this book is an archival reference guide for researchers, engineers, scientists and postgraduates working in the field of sustainable science, green chemistry, environmental science, engineering sciences and industrial technologies.

Author: Ashutosh Kumar Shukla
Publisher: Elsevier
ISBN: 0081025807
Category : Technology & Engineering
Languages : en
Pages : 548

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Book Description
Green Synthesis, Characterization and Applications of Nanoparticles shows how eco-friendly nanoparticles are engineered and used. In particular, metal nanoparticles, metal oxide nanoparticles and other categories of nanoparticles are discussed. The book outlines a range of methodologies and explores the appropriate use of each. Characterization methods include spectroscopic, microscopic and diffraction methods, but magnetic resonance methods are also included as they can be used to understand the mechanism of nanoparticle synthesis using organisms. Applications covered include targeted drug delivery, water purification and hydrogen generation. This is an important research resource for those wishing to learn more about how eco-efficient nanoparticles can best be used. Theoretical details and mathematical derivations are kept to a necessary minimum to suit the need of interdisciplinary audiences and those who may be relatively new to the field. Explores recent trends in growth, characterization, properties and applications of nanoparticles Gives readers an understanding on how they are applied through the use of case studies and examples Assesses the advantages and disadvantages of a variety of synthesis and characterization techniques for green nanoparticles in different situations

Author: Emily A. Peterson
Publisher: Royal Society of Chemistry
ISBN: 1849739617
Category : Medical
Languages : en
Pages : 338

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Book Description
The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Edited by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Currently employed as well as emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery. Moreover, important surrounding issues such as intellectual property are included. This book will serve as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.

Author: Garg, Rajni
Publisher: IGI Global
ISBN: 1799889386
Category : Technology & Engineering
Languages : en
Pages : 569

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Book Description
Nanomaterials can be synthesized by physical, chemical, and biological methods; however, the latter technique is preferred as it is eco-friendly, non-toxic, and cost-effective. The green synthesized nanomaterials have been found to be more efficient with potential applications in diverse fields. It is crucial to explore green synthesized nanomaterials and the applications that can be made in order to support water remediation, pharmaceuticals, food processing, construction, and more. The Handbook of Research on Green Synthesis and Applications of Nanomaterials provides a multidisciplinary approach to the awareness of using non-toxic, eco-friendly, and economical green techniques for the synthesis of various nanomaterials, as well as their applications across a variety of fields. Covering topics such as antimicrobial applications, environmental remediation, and green synthesis, this book acts as a thorough reference for engineers, nanotechnology professionals, academicians, students, scientists, and researchers pursuing research in the nanotechnology field.