Author: Carlos A. Vaccaro
Publisher: Frontiers Media SA
ISBN: 2832512127
Category : Medical
Languages : en
Pages : 108

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Book Description

Author: Jorge Melendez-Zajgla
Publisher: Frontiers Media SA
ISBN: 2832536115
Category : Medical
Languages : en
Pages : 135

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Book Description

Author: John D. Potter
Publisher: Springer
ISBN: 9780387095677
Category : Medical
Languages : en
Pages : 309

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Book Description
Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.

Author: Miguel A. Rodriguez-Bigas
Publisher: Springer Science & Business Media
ISBN: 144196603X
Category : Medical
Languages : en
Pages : 615

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Book Description
Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

Author: Laura Valle
Publisher: Springer
ISBN: 3319742590
Category : Medical
Languages : en
Pages : 505

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Book Description
This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.

Author: F. T. Bosman
Publisher: International Agency for Research on Cancer
ISBN:
Category : Medical
Languages : en
Pages : 424

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Book Description
"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].

Author: Graeme P. Young
Publisher: W.B. Saunders Company
ISBN:
Category : Medical
Languages : en
Pages : 410

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Book Description
This is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors.

Author: Sam Thiagalingam
Publisher: Cambridge University Press
ISBN: 0521493390
Category : Mathematics
Languages : en
Pages : 597

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Book Description
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Author: Naveen Kumar Vishvakarma
Publisher: Springer Nature
ISBN: 3030646688
Category : Medical
Languages : en
Pages : 453

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Book Description
Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

Author: Kenneth W. Kinzler
Publisher: McGraw Hill Professional
ISBN: 9780071370509
Category : Cancer
Languages : en
Pages : 358

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Book Description
-- Current coverage of diagnosis and treatment on a wide spectrum of active cancer research.