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Advances in Computational Biology

Advances in Computational Biology PDF Author: H.O. Villar
Publisher: Elsevier
ISBN: 008052611X
Category : Science
Languages : en
Pages : 281

Book Description
The second volume in a series which aims to focus on advances in computational biology. This volume discusses such topics as: statistical analysis of protein sequences; progress in large-scale sequence analysis; and the architecture of loops in proteins.

Advances in Computational Biology

Advances in Computational Biology PDF Author: H.O. Villar
Publisher: Elsevier
ISBN: 008052611X
Category : Science
Languages : en
Pages : 281

Book Description
The second volume in a series which aims to focus on advances in computational biology. This volume discusses such topics as: statistical analysis of protein sequences; progress in large-scale sequence analysis; and the architecture of loops in proteins.

Advances in Computational and Bio-Engineering

Advances in Computational and Bio-Engineering PDF Author: S. Jyothi
Publisher: Springer Nature
ISBN: 3030469395
Category : Mathematics
Languages : en
Pages : 650

Book Description
This book gathers state-of-the-art research in computational engineering and bioengineering to facilitate knowledge exchange between various scientific communities. Computational engineering (CE) is a relatively new discipline that addresses the development and application of computational models and simulations often coupled with high-performance computing to solve complex physical problems arising in engineering analysis and design in the context of natural phenomena. Bioengineering (BE) is an important aspect of computational biology, which aims to develop and use efficient algorithms, data structures, and visualization and communication tools to model biological systems. Today, engineering approaches are essential for biologists, enabling them to analyse complex physiological processes, as well as for the pharmaceutical industry to support drug discovery and development programmes.

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology PDF Author: Hamid R Arabnia
Publisher: Morgan Kaufmann
ISBN: 0128026464
Category : Computers
Languages : en
Pages : 670

Book Description
Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. - Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. - Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. - Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.

Computational Methods for Understanding Bacterial and Archaeal Genomes

Computational Methods for Understanding Bacterial and Archaeal Genomes PDF Author: Ying Xu
Publisher: World Scientific
ISBN: 1860949827
Category : Medical
Languages : en
Pages : 494

Book Description
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.

Kernel Methods in Computational Biology

Kernel Methods in Computational Biology PDF Author: Bernhard Schölkopf
Publisher: MIT Press
ISBN: 9780262195096
Category : Computers
Languages : en
Pages : 428

Book Description
A detailed overview of current research in kernel methods and their application to computational biology.

Introduction to Computational Biology

Introduction to Computational Biology PDF Author: Michael S. Waterman
Publisher: CRC Press
ISBN: 1351437089
Category : Mathematics
Languages : en
Pages : 456

Book Description
Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.

Computational Biology and Bioinformatics

Computational Biology and Bioinformatics PDF Author: Ka-Chun Wong
Publisher: CRC Press
ISBN: 1498725007
Category : Science
Languages : en
Pages : 439

Book Description
The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analy

Computational Structural Biology

Computational Structural Biology PDF Author: Torsten Schwede
Publisher: World Scientific
ISBN: 9812778780
Category : Science
Languages : en
Pages : 790

Book Description
This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.

Current Topics in Computational Molecular Biology

Current Topics in Computational Molecular Biology PDF Author: Tao Jiang
Publisher: MIT Press
ISBN: 9780262100922
Category : Computers
Languages : en
Pages : 570

Book Description
A survey of current topics in computational molecular biology. Computational molecular biology, or bioinformatics, draws on the disciplines of biology, mathematics, statistics, physics, chemistry, computer science, and engineering. It provides the computational support for functional genomics, which links the behavior of cells, organisms, and populations to the information encoded in the genomes, as well as for structural genomics. At the heart of all large-scale and high-throughput biotechnologies, it has a growing impact on health and medicine. This survey of computational molecular biology covers traditional topics such as protein structure modeling and sequence alignment, and more recent ones such as expression data analysis and comparative genomics. It combines algorithmic, statistical, database, and AI-based methods for studying biological problems. The book also contains an introductory chapter, as well as one on general statistical modeling and computational techniques in molecular biology. Each chapter presents a self-contained review of a specific subject. Not for sale in China, including Hong Kong.

An Introduction to Computational Systems Biology

An Introduction to Computational Systems Biology PDF Author: Karthik Raman
Publisher: CRC Press
ISBN: 0429944527
Category : Computers
Languages : en
Pages : 359

Book Description
This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks—a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Key Features: A hands-on approach to modelling Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design Emphasis on coding and software tools for systems biology Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https://ramanlab.github.io/SysBioBook/ An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others.