Blood Substitutes, Present and Future Perspectives PDF Download

Author: E. Tsuchida
Publisher: Elsevier
ISBN: 008052821X
Category : Science
Languages : en
Pages : 409

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Book Description
This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. In keeping with the scientific design of the 7th ISBS Symposium, chapters have been carefully selected and organized to showcase the advancements in recent research. This book includes up-to-date clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes, and covers issues of hemoglobin toxicity and side effects such as vasoconstriction in more detail using carefully designed in vivo and ex vivo techniques. This book is also a collection of various new types of red cell substitutes such as recombinant Hbs, recombinant albumine-lipidheme complex, modified red blood cells, and perfluorochemicals using material science and molecular engineering.

Author: Forum on Blood Safety and Blood Availability
Publisher: National Academies Press
ISBN: 0309589622
Category : Medical
Languages : en
Pages : 132

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Book Description
This volume discusses the current state of the nation's blood supply--including studies of blood availability, ways of enhancing blood collection and distribution, frozen red cell technology, logistical concerns in prepositioning frozen blood, extended liquid storage of red cells, and blood substitutes.

Author: R. Winslow
Publisher: Springer Science & Business Media
ISBN: 1461219760
Category : Medical
Languages : en
Pages : 351

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Book Description
Each chapter of this volume is a contribution from an expert in the field, chosen by the editors to contribute to the 1997 "Current Issues in Blood Substitute Research and Development" course given in San Diego, March 17-19. The contributors were selected because of their expertise in areas which the editors believe to be critical to the advancement of the field, and which reflect activity in "hot" areas of relevant research. While there is a continuity in style for the annual course, each year brings changes in emphasis and content. In previous years, we were often not able to provide time for participants to present their views and opinions. Consequently, this year we encouraged discussion after each presentation. These sessions were recorded, transcribed, and are printed with the chapters herein. We believe that the product is very close to the capturing this year's course in print, and trust readers will enjoy reading the always candid and often provocative remarks from the audience. The price paid for inclusion of the discussion transcriptions was a delay in publication. Each author was allowed to edit his/her discussion section as well as the final version of the chapters prior to publication. The changes are mainly for grammar, and we tried, when possible, not to alter the conversational style of these interchanges.

Author: Hae Won Kim
Publisher: Springer Science & Business Media
ISBN: 364240717X
Category : Technology & Engineering
Languages : en
Pages : 741

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Book Description
Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects.

Author: Harvey G. Klein
Publisher: John Wiley & Sons
ISBN: 0470986859
Category : Medical
Languages : en
Pages : 923

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Book Description
“Both authors have dealt in an authoritative way withthe still rapidly expanding specialty and the eleventh edition ofthe book will be of the greatest value to all who are interested inthe scientific and practical aspects of blood transfusion inclinical medicine.” From the Foreword by Professor P.L. Mollison Highly respected, long-established book that has become the"bible" in transfusion medicine Why Buy This Book? Provides a sound basis for understanding modern transfusionmedicine Definitive reference source for any clinician involved withpatients requiring transfusion and for all staff working intransfusion services, immunohaematology laboratories and bloodbanks Highly practical advice on management issues for theclinician Completely revised and updated to reflect the rapid pace ofchange in transfusion medicine Written by two of the world's leading experts in the field

Author: Adil Denizli
Publisher: Elsevier
ISBN: 0128241802
Category : Technology & Engineering
Languages : en
Pages : 495

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Book Description
Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood outlines the fundamental design concepts and emerging applications of nanotechnology in hematology, blood transfusion and artificial blood. This book is an important reference source for materials scientists, engineers and biomedical scientists who are looking to increase their understanding of how nanotechnology can lead to more efficient blood treatments. Sections focus on how nanotechnology could offer new routes to address challenging and pressing issues facing rare blood diseases and disorders and how nanomaterials can be used as artificial cell-like systems (compartmentalized biomimetic nanocontainers), which are especially useful in drug delivery. For artificial blood, the nanotechnological approach can fabricate artificial red blood cells, platelet substitutes, and white blood cell substitutes with their inherent enzyme and other supportive systems. In addition, nanomaterials can promote blood vessel growth and reserve red blood cells at a positive temperature. - Provides information on how nanotechnology can be used to create more efficient solutions for blood transfusions and hematology treatments - Explores the major nanomaterial types that are used for these treatments - Assesses the major challenges of using nanomaterials hematology

Author: James E. Cottrell
Publisher: Elsevier Health Sciences
ISBN: 0323086314
Category : Medical
Languages : en
Pages : 481

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Book Description
Cottrell's Neuroanesthesia 5th Edition, edited by James E. Cottrell, MD, FRCA and William L. Young, MD, delivers the complete and authoritative guidance you need to ensure optimal perioperative safety for neurosurgical patients. Integrating current scientific principles with the newest clinical applications, it not only explains what to do under any set of circumstances but also why to do it and how to avoid complications. Comprehensive updates reflect all of the latest developments in neurosurgical anesthesia, and contributions from many new experts provide fresh insights into overcoming tough clinical challenges. New co-editor William L. Young, MD joins James E. Cottrell, MD, FRCA at the book's editorial helm, providing additional, complementary expertise and further enhancing the book's authority. New chapters keep you current on interventional neuroradiology, anesthetic management of patients with arteriovenous malformations and aneurysms, awake craniotomy, epilepsy, minimally invasive and robotic surgery, and pregnancy and neurologic disease. Comprehensive updates reflect all of the latest developments in neurosurgical anesthesia, and contributions from many new experts provide fresh insights into overcoming tough clinical challenges. Comprehensive and broad coverage of all important aspects of neuroanesthesia, including special patient populations, enables you to find reliable answers to any clinical question. Chapters written by neurointensivists, neurosurgeons, and radiologists provide well-rounded perspectives on each topic. A consistent, logical organization to every chapter makes answers easy to find quickly. Clear conceptual illustrations make complex concepts easier to understand at a glance.

Author: Susan Cotter
Publisher: Academic Press
ISBN: 0323154433
Category : Science
Languages : en
Pages : 358

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Book Description
Comparative Transfusion Medicine describes the role of animals as donors in early human transfusions. Organized into 11 chapters, the book focuses on specific animal models of human hematologic diseases. After briefly dealing with the history of transfusion in medicine, the book discusses erythrocytes, white cells, platelets, and coagulation in various animal species, and then describes specific animal models of human hematologic diseases. It then considers the progress in bone marrow transplantation by pioneering histocompatibility studies of dogs. The discussion then shifts to the preparation components and clinical veterinary transfusions. The book also presents three problems in neonatal transfusion, including the failure of passive transfer, isoerythrolysis, and immunotherapy. The concluding chapters explore the developments in human autologous transfusion, blood substitutes, and hematopoietic growth factors. The book is of great value to veterinarians involved in research or in clinical transfusions, and to physicians and other scientists using animals in research.

Author: Wiley W. Souba
Publisher: Academic Press
ISBN: 9780126553307
Category : Health & Fitness
Languages : en
Pages : 1526

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Book Description
Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...

Author: R. Winslow
Publisher: Springer Science & Business Media
ISBN: 9780817639808
Category : Medical
Languages : en
Pages : 360

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Book Description
Each chapter of this volume is a contribution from an expert in the field, chosen by the editors to contribute to the 1997 "Current Issues in Blood Substitute Research and Development" course given in San Diego, March 17-19. The contributors were selected because of their expertise in areas which the editors believe to be critical to the advancement of the field, and which reflect activity in "hot" areas of relevant research. While there is a continuity in style for the annual course, each year brings changes in emphasis and content. In previous years, we were often not able to provide time for participants to present their views and opinions. Consequently, this year we encouraged discussion after each presentation. These sessions were recorded, transcribed, and are printed with the chapters herein. We believe that the product is very close to the capturing this year's course in print, and trust readers will enjoy reading the always candid and often provocative remarks from the audience. The price paid for inclusion of the discussion transcriptions was a delay in publication. Each author was allowed to edit his/her discussion section as well as the final version of the chapters prior to publication. The changes are mainly for grammar, and we tried, when possible, not to alter the conversational style of these interchanges.