Author: Sydney E. SalmonPublisher: Lippincott Williams & Wilkins
ISBN: 9780397584437
Category : Medical
Languages : en
Pages : 298
Book Description
Adjuvant Therapy of Cancer VIII
Author: Sydney E. SalmonPublisher: Lippincott Williams & Wilkins
ISBN: 9780397584437
Category : Medical
Languages : en
Pages : 298
Book Description
Adjuvant Therapy of Cancer VIII
Author: Sydney E. SalmonPublisher: Lippincott Williams & Wilkins
ISBN: 9780397584437
Category : Medical
Languages : en
Pages : 330
Book Description
Adjuvant Therapies of Cancer
Author: Georges Mathe;&AAe;Publisher: Springer Science & Business Media
ISBN: 3642816851
Category : Medical
Languages : en
Pages : 404
Book Description
Transplantation of syngeneic (donor is a monozygous twin) or allogeneic (donor is an HLA-identical sibling) marrow provides the opportunity for aggressive antileukemic therapy without regard to marrow toxicity. Until 1975, marrow transplantation was carried out only after failure of all other therapy. Consequently, most patients were in advanced relapse. Six of 16 recipients of syngeneic marrow and 13 of 100 recipients of allogeneic marrow are still in remission after 5. 5-10 years [3, 7]. An actuarial survival curve of the first 100 patients grafted in Seattle after conditioning with cyclophos phamide (60 mg/kg on each of 2 successive days) and total body irradiation (1,000 rad) showed three periods of interest: (1) The first 4 months showed a rapid loss of patients associated with advanced illness, graft-versus-host disease, infections (in particular interstitial pneumonias), and recurrent leukemia; (2) from 4 months to 2 years, the curve showed a much slower rate of decline attributable primarily to recurrent leukemia; and (3) from 2-10 years, the curve was almost flat with a negligible loss of patients and no recurrent leukemia. This flat portion of the curve corresponded to 13% of the patients and indicates a strong probability that the majority of these survivors are cured of their disease [8]. Attempts at reducing the incidence of leukemic relapse after transplantation were made by a number of marrow transplant groups by added chemotherapy.
Rectal Cancer Treatment
Author: M.W. BüchlerPublisher: Springer Science & Business Media
ISBN: 3540274499
Category : Medical
Languages : en
Pages : 284
Book Description
Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.
Adjuvant Therapy of Cancer
Author: Sunlight, Vitamin D and Skin Cancer
Author: Jörg ReichrathPublisher: Springer Nature
ISBN: 3030462277
Category : Medical
Languages : en
Pages : 428
Book Description
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
Preoperative (Neoadjuvant) Chemotherapy
Author: Joseph RagazPublisher: Springer Science & Business Media
ISBN: 3642826717
Category : Medical
Languages : en
Pages : 172
Book Description
Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.
AJCC Cancer Staging Manual
Author: Frederick L, GreenePublisher: Springer Science & Business Media
ISBN: 1475736568
Category : Medical
Languages : en
Pages : 386
Book Description
The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.
Melanoma in Clinical Practice
Author: Rhoda M. AlaniPublisher: Springer
ISBN: 9783030826383
Category : Medical
Languages : en
Pages : 363
Book Description
This book provides a concise practical guide to melanoma enabling the reader to develop a thorough understanding of the etiology, pathogenesis, diagnosis, treatment and prevention of melanoma. It features easy to digest instructional text that describes a variety of techniques for detecting and staging melanoma including total body photography. Surgical, radiation and systemic therapy treatment options as well as prevention strategies are also covered. Melanoma in Clinical Practice represents a thorough guide on how to diagnose treat and prevent melanoma, and provides a valuable resource for the trainee and experienced clinical dermatologists who are seeking a reference guide to use in their clinical practice.
Author: