Active Implants and Scaffolds for Tissue Regeneration PDF Download

Author: Meital Zilberman
Publisher: Springer Science & Business Media
ISBN: 3642180655
Category : Technology & Engineering
Languages : en
Pages : 511

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Book Description
Active implants are actually drug or protein-eluting implants that induce healing effects, in addition to their regular task, such as support. This effect is achieved by controlled release of the active agent to the surrounding tissue. This book will give a broad overview of biomaterial platforms used as basic elements of drug-eluting implants. It will include mainly coatings for vascular stents with controlled release of antiproliferative agents, wound dressings with controlled release of antibacterial agents, drug-eluting vascular grafts, protein-eluting scaffolds for tissue regeneration, drug-eluting platforms for dental and other applications. Thus, both internal and external implants are described. The drug-eluting implants will be described in terms of matrix formats and polymers, incorporated drugs and their release profiles from the implants, as well as implant functioning. Smart polymeric systems, such as crosslinked poly-lactones, thermo and pH-sensitive hydrogels and poly(amido-amines), as well as novel basic structural elements, such as composite fibers and films, and nanostructures will be thoroughly described. The effect of the processing parameters on the microstructure and on the resulting drug release profiles, mechanical and physical properties, and other relevant properties, will be emphasized. The described new biomaterials approaches for active implants enhance the tools available for creating clinically important biomedical applications.

Author: Qing Li
Publisher: Springer
ISBN: 3662535742
Category : Technology & Engineering
Languages : en
Pages : 472

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Book Description
This book highlights the latest, cutting-edge advances in implantable biomaterials. It brings together a class of advanced biomaterials in two highly active research areas, namely implants and tissue scaffolds, to underline their respective functional requirements for further development. It is unique in providing a full range of methodological procedures, including materials syntheses, characterisation, cellular tests and mathematical modelling. Covering metallic, ceramic, polymeric and composite materials commonly used in biological applications and clinical therapeutics, it is a valuable resource for anyone wanting to further their understanding of the latest developments in implantable biomaterials. Focusing on biomedical applications in implants and scaffolds, it provides methodological guides to this rapidly growing field. Qing Li and Yiu-Wing Mai are both professors at the University of Sydney, School of Aerospace, Mechanical and Mechatronic Engineering.

Author: James V. Quinn
Publisher: PMPH-USA
ISBN: 9781550092820
Category : Medical
Languages : en
Pages : 196

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Book Description
This second edition has expanded the scope and depth of the original text and includes all types of tissue adhesives, their proper indications and their uses. It also adds a final chapter on regulatory issues that contains FDA scientist George Mattamal's perspectives on all adhesives now used clinically or being evaluated by the FDA. The contributors address topics such as the history and background of tissue adhesives, clinical approaches to the use of cyanoacrylate tissue adhesives, protein polymers, and bone cements. The CD-ROM accompanying the book features video demonstrations of techniques. Annotation : 2005 Book News, Inc., Portland, OR (booknews.com).

Author: Jeffrey O. Hollinger
Publisher: CRC Press
ISBN: 1135501912
Category : Medical
Languages : en
Pages : 462

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Book Description
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Author: Naznin Sultana
Publisher: CRC Press
ISBN: 0429749627
Category : Technology & Engineering
Languages : en
Pages : 185

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Book Description
Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

Author: Ilser Turkyilmaz
Publisher: BoD – Books on Demand
ISBN: 9535117416
Category : Medical
Languages : en
Pages : 278

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Book Description
Implant dentistry has changed and enhanced significantly since the introduction of osseointegration concept with dental implants. Because the benefits of therapy became apparent, implant treatment earned a widespread acceptance. Therefore, the need for dental implants has caused a rapid expansion of the market worldwide. Dental implantology continues to excel with the developments of new surgical and prosthodontic techniques, and armamentarium. The purpose of this book named Current Concepts in Dental Implantology is to present a novel resource for dentists who want to replace missing teeth with dental implants. It is a carefully organized book, which blends basic science, clinical experience, and current and future concepts. This book includes ten chapters and our aim is to provide a valuable source for dental students, post-graduate residents and clinicians who want to know more about dental implants.

Author: Gokare A. Ravishankar
Publisher: CRC Press
ISBN: 0429623437
Category : Science
Languages : en
Pages : 345

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Book Description
Key features: The most comprehensive resource available on the biodiversity of algal species, their industrial production processes and their use for human consumption in food, health and varied applications. Emphasis on basic and applied research, addressing aspects of scale-up for commercial exploitation for the development of novel phytochemicals (phytochemicals from algae). Addresses the underexplored and underutilized potential of chemicals from marine sources for health benefits. Each chapter, written by expert contributors from around the world, includes Summary Points, Figures and Tables, as well as up-to-date references. The first book in this two-volume set explores the diversity of algal constituents for health and disease applications. The commercial value of chemicals of value to food and health is about $6 billion annually, of which 30 percent relates to micro and macro algal metabolites and products for health food applications. This comprenhensive volume looks in detail at algal genomics and metabolomics as well as mass production of microalgae. As a whole, the two-volume set covers all micro and macro algal forms and their traditional uses; their constituents which are of value for food, feed, specialty chemicals, bioactive compounds for novel applications, and bioenergy molecules. Bio-business and the market share of algae-based products are also dealt with, providing global perspectives.

Author: SuPing Lyu
Publisher: John Wiley & Sons
ISBN: 1118120000
Category : Technology & Engineering
Languages : en
Pages : 288

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Book Description
This book covers two areas, the first detailing the concepts and technologies of drug-device combination products. The second area includes case studies of important products that either significantly shape our technologies and thinking, or contribute to current healthcare practice. The book: Discusses where drugs and devices work, where they fail, and when they need to work with each other Reviews interactions between human bodies and the drug-device combination products the measurements of these interactions Covers how a drug-device combination product is developed, tested, and regulated Includes case studies of steroid releasing leads, AOA treated tissue heart valves, intrathecal drug delivery pumps, infuse bone grafts, drug eluting stents, and antimicrobial meshes

Author: Gianni Ciofani
Publisher: Elsevier
ISBN: 0128141573
Category : Technology & Engineering
Languages : en
Pages : 270

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Book Description
Smart Nanoparticles for Biomedicine explores smart nanoparticles that change their structural or functional properties in response to specific external stimuli (electric or magnetic fields, electromagnetic radiation, ultrasound, etc.). Particular attention is given to multifunctional nanostructured materials that are pharmacologically active and that can be actuated by virtue of their magnetic, dielectric, optically-active, redox-active, or piezoelectric properties. This important reference resource will be of great value to readers who want to learn more on how smart nanoparticles can be used to create more effective treatment solutions. Nanotechnology has enabled unprecedented control of the interactions between materials and biological entities, from the microscale, to the molecular level. Nanosurfaces and nanostructures have been used to mimic or interact with biological microenvironments, to support specific biological functions, such as cell adhesion, mobility and differentiation, and in tissue healing. Recently, a new paradigm has been proposed for nanomedicine to exploit the intrinsic properties of nanomaterials as active devices rather than as passive structural units or carriers for medications. - Discusses the synthesis, characterization and applications of a new generation of smart nanoparticles for nanomedicine applications - Explores the problems relating to the biocompatibility of a range of nanoparticles, outlining potential solutions - Describes techniques for manipulating specific classes of nanoparticles for a variety of treatment types

Author: Sougata Jana
Publisher: John Wiley & Sons
ISBN: 3527848118
Category : Technology & Engineering
Languages : en
Pages : 983

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Book Description
Revolutionize the search for sustainable industry with these biodegradable materials The search for biodegradable materials has become an increasingly essential component of the global response to climate change and the urgent need for more sustainable industrial processes. Biodegradable polymers, either synthetic or natural, have become an explosive research subject as their applications in food, medicinal, and pharmaceutical industries become more and more apparent. There is an urgent need for chemists and other professionals working in these industries to understand the range of available biopolymers and how to use them. Biopolymers in Pharmaceutical and Food Applications presents an overview of all currently-known food-safe polymers and their applications for food and pharmaceutical technology. Its grasp of recent sustainable trends in biopolymer production and distribution make it a one-stop shop for researchers and industry professionals looking to understand the future of sustainable food production, pharmaceutical and cosmetic applications. Comprehensive and accessible, it has never been timelier as a contribution to these key industries. Readers of the two volumes of Biopolymers in Pharmaceutical and Food Applications will also find: Treatment of biopolymers including collagen, chitosan, carrageenan, and more Detailed discussion of drug delivery systems incorporating plant- and animal-based biopolymers An editor with extensive research and teaching experience in biopolymer and pharmaceutical research Biopolymers in Pharmaceutical and Food Applications is ideal for polymer chemists, pharmaceutical chemists, food scientists, and any other researcher looking to work with biodegradable polymers.