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Author: Rebecca C. Thompson Publisher: MIT Press ISBN: 0262043076 Category : Science Languages : en Pages : 297
Book Description
Exploring the science in George R. R. Martin's fantastical world, from the physics of an ice wall to the genetics of the Targaryens and Lannisters. Game of Thrones is a fantasy that features a lot of made-up science—fabricated climatology (when is winter coming?), astronomy, metallurgy, chemistry, and biology. Most fans of George R. R. Martin's fantastical world accept it all as part of the magic. A trained scientist, watching the fake science in Game of Thrones, might think, “But how would it work?” In Fire, Ice, and Physics, Rebecca Thompson turns a scientist's eye on Game of Thrones, exploring, among other things, the science of an ice wall, the genetics of the Targaryen and Lannister families, and the biology of beheading. Thompson, a PhD in physics and an enthusiastic Game of Thrones fan, uses the fantasy science of the show as a gateway to some interesting real science, introducing GOT fandom to a new dimension of appreciation. Thompson starts at the beginning, with winter, explaining seasons and the very elliptical orbit of the Earth that might cause winter to come (or not come). She tells us that ice can behave like ketchup, compares regular steel to Valyrian steel, explains that dragons are “bats, but with fire,” and considers Targaryen inbreeding. Finally she offers scientific explanations of the various types of fatal justice meted out, including beheading, hanging, poisoning (reporting that the effects of “the Strangler,” administered to Joffrey at the Purple Wedding, resemble the effects of strychnine), skull crushing, and burning at the stake. Even the most faithful Game of Thrones fans will learn new and interesting things about the show from Thompson's entertaining and engaging account. Fire, Ice, and Physics is an essential companion for all future bingeing.
Author: Rebecca C. Thompson Publisher: MIT Press ISBN: 0262043076 Category : Science Languages : en Pages : 297
Book Description
Exploring the science in George R. R. Martin's fantastical world, from the physics of an ice wall to the genetics of the Targaryens and Lannisters. Game of Thrones is a fantasy that features a lot of made-up science—fabricated climatology (when is winter coming?), astronomy, metallurgy, chemistry, and biology. Most fans of George R. R. Martin's fantastical world accept it all as part of the magic. A trained scientist, watching the fake science in Game of Thrones, might think, “But how would it work?” In Fire, Ice, and Physics, Rebecca Thompson turns a scientist's eye on Game of Thrones, exploring, among other things, the science of an ice wall, the genetics of the Targaryen and Lannister families, and the biology of beheading. Thompson, a PhD in physics and an enthusiastic Game of Thrones fan, uses the fantasy science of the show as a gateway to some interesting real science, introducing GOT fandom to a new dimension of appreciation. Thompson starts at the beginning, with winter, explaining seasons and the very elliptical orbit of the Earth that might cause winter to come (or not come). She tells us that ice can behave like ketchup, compares regular steel to Valyrian steel, explains that dragons are “bats, but with fire,” and considers Targaryen inbreeding. Finally she offers scientific explanations of the various types of fatal justice meted out, including beheading, hanging, poisoning (reporting that the effects of “the Strangler,” administered to Joffrey at the Purple Wedding, resemble the effects of strychnine), skull crushing, and burning at the stake. Even the most faithful Game of Thrones fans will learn new and interesting things about the show from Thompson's entertaining and engaging account. Fire, Ice, and Physics is an essential companion for all future bingeing.
Author: Jong Hoon Park Publisher: Springer ISBN: 9811020418 Category : Medical Languages : en Pages : 128
Book Description
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Author: Thomas Liehr Publisher: Academic Press ISBN: 0128235802 Category : Science Languages : en Pages : 430
Book Description
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book's second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. - Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies - Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease - Features chapter contributions from international leaders in the field
Author: Paul C. Cozby Publisher: WCB/McGraw-Hill ISBN: Category : Psychology Languages : en Pages : 300
Book Description
For undergradute social science majors. A textbook on the interpretation and use of research. Annotation copyright Book News, Inc. Portland, Or.
Author: Dino Borri Publisher: Springer Science & Business Media ISBN: 9780792343264 Category : Technology & Engineering Languages : en Pages : 276
Book Description
This volume contains a selection of papers presented at the second workshop on Evaluation and Planning held at Centre International de Hautes Etudes Agronomiques Mediterraneennes (CIHEAM) in Valenzano (Bari) in November 1993. The workshop was financially and otherwise supported by the School of Engineering, Bari Polytechnic; the School of Agriculture, University of Bari; and CIHEAM. The publication of this book was made possible by to the efforts of the contributing authors. Several other persons have provided invaluable support for the workshop or the preparation of this volume. One of these is Patsy Healey for her fascinating challenge to Andreas Faludi's most recent arguments about rational planning theory. Another is John Friedmann whose lecture at the workshop presented world future scenarios depicting interaction between economic growth, social justice and ecological balance. Angela Barbanente provided marvelous support in organizing the workshop and editorial advice in the preparation of this volume. Jeremy Franks carefully improved the English and the clarity of all the papers. Carmelo Torre made a final editing of texts and images. We owe thanks to Maurizio Raeli for providing all the support services during the workshop and Claudia Baublys for her excellent help with various administrative issues with regard to the workshop and publication of this book. This book is dedicated to the memory of Professor Giovanni Grittani, Professor of Land Economics, University of Bari.
Author: Kenneth A. Gould Publisher: Oxford University Press, USA ISBN: 9780190088514 Category : SCIENCE Languages : en Pages : 432
Book Description
New to this Edition: Completely new lessons on "Theories in Environmental Sociology" (Lesson 2), "The Sociology of Environmental Health" (Lesson 11), and "Environmental Social Movements" (Lesson 18), written by new contributors, A brand new lesson on "Climate Change" (Lesson 15), written by a new contributor, A greater focus on issues of gender inequality and Indigenous peoples throughout, Updated data and examples in lessons, An invitation from the authors for students to post photos that represent the book's themes on social media, using hashtags linked to the book, An Instructor's Manual, available to all adopters, contains Discussion Questions, Suggested Media, and Additional Readings for each lesson. Book jacket.
Author: Jeff Ollerton Publisher: Pelagic Publishing Ltd ISBN: 1784272299 Category : Science Languages : en Pages : 425
Book Description
A unique and personal insight into the ecology and evolution of pollinators, their relationships with flowers, and their conservation in a rapidly changing world. The pollination of flowers by insects, birds and other animals is a fundamentally important ecological function that supports both the natural world and human society. Without pollinators to facilitate the sexual reproduction of plants, the world would be a biologically poorer place in which to live, there would be an impact on food security, and human health would suffer. Written by one of the world’s leading pollination ecologists, this book provides an introduction to what pollinators are, how their interactions with flowers have evolved, and the fundamental ecology of these relationships. It explores the pollination of wild and agricultural plants in a variety of habitats and contexts, including urban, rural and agricultural environments. The author also provides practical advice on how individuals and organisations can study, and support, pollinators. As well as covering the natural history of pollinators and flowers, the author discusses their cultural importance, and the ways in which pollinator conservation has been portrayed from a political perspective. The book draws on field work experiences in South America, Africa, Australia, the Canary Islands and the UK. For over 30 years the author has spent his career researching how plants and pollinators evolve relationships, how these interactions function ecologically, their importance for society, and how we can conserve them in a rapidly changing world. This book offers a unique and personal insight into the science of pollinators and pollination, aimed at anyone who is interested in understanding these fascinating and crucial ecological interactions.
Author: Rebecca C. Thompson
Author: Rebecca C. Thompson
Author: Jong Hoon Park
Author: British Library. Lending Division
Author: Thomas Liehr
Author: Paul C. Cozby
Author: Dino Borri
Author: James Robert Douglass
Author: Kenneth A. Gould
Author: Jeff Ollerton
Author: Entomological Society of British Columbia