Absorbable Metals for Biomedical Applications PDF Download

Author: Hendra Hermawan
Publisher:
ISBN: 9783036517643
Category :
Languages : en
Pages : 256

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Book Description
Absorbable metals have shown significant clinical potential for temporary implant applications, where the material is eventually replaced by healthy, functioning tissue. However, several challenges remain before these metals can be used in humans. Innovations and further improvements are required. This book collects scientific contributions dealing with the development of absorbable metals with improved and unique corrosion and mechanical properties for applications in highly loaded implants or cardiovascular and urethral stents.

Author: Mitsuo Niinomi
Publisher: Elsevier
ISBN: 1845699246
Category : Technology & Engineering
Languages : en
Pages : 439

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Book Description
Despite recent advances in medical devices using other materials, metallic implants are still one of the most commercially significant sectors of the industry. Given the widespread use of metals in medical devices, it is vital that the fundamentals and behaviour of this material are understood. Metals in biomedical devices reviews the latest techniques in metal processing methods and the behaviour of this important material. Initial chapters review the current status and selection of metals for biomedical devices. Chapters in part two discuss the mechanical behaviour, degradation and testing of metals with specific chapters on corrosion, wear testing and biocompatibility of biomaterials. Part three covers the processing of metals for biomedical applications with chapters on such topics as forging metals and alloys, surface treatment, coatings and sterilisation. Chapters in the final section discuss clinical applications of metals such as cardiovascular, orthopaedic and new generation biomaterials. With its distinguished editor and team of expert contributors, Metals for biomedical devices is a standard reference for materials scientists, researchers and engineers working in the medical devices industry and academia. Reviews the latest techniques in metal processing methods including surface treatment and sterilisation Examines metal selection for biomedical devices considering biocompatibility of various metals Assesses mechanical behaviour and testing of metals featuring corrosion, fatigue and wear

Author: Mitsuo Niinomi
Publisher: Woodhead Publishing
ISBN: 0081026676
Category : Medical
Languages : en
Pages : 596

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Book Description
Metals for Biomedical Devices, Second Edition, has been fully updated and builds upon the success of its first edition, discussing the latest techniques in metal processing methods and the behavior of this important material. Initial chapters review the current status and selection of metals for biomedical devices. Subsequent chapters cover mechanical behavior, degradation and testing, corrosion, wear testing and biocompatibility, the processing of metals for biomedical applications, including topics such as forging metals and alloys, surface treatment, coatings and sterilization. Chapters in the final section discuss the clinical applications of metals, such as cardiovascular, orthopedic and new generation biomaterials. With its distinguished editor and team of expert contributors, this book is a standard reference for materials scientists, researchers and engineers working in the medical devices industry and academia. Reviews the latest techniques in metal processing methods, including surface treatment and sterilization Examines metal selection for biomedical devices, considering the biocompatibility of various metals Assesses mechanical behavior and the testing of metals, featuring the latest information on corrosion, fatigue and wear Discusses biodegradable alloys, including a new section on Mg alloys Includes a new section that discusses the use of additive manufacturing in the production of medical devices

Author: Mahendra Rai
Publisher: Springer
ISBN: 3319748149
Category : Medical
Languages : en
Pages : 332

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Book Description
Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the development of novel therapeutic products and solutions in the form of alternative medicines, and some topics on Indian traditional medicine i.e., “Ayurveda”. In Section I, the book discusses the role of metals in medicines and include chapters on nanoparticles, noble metals, medical devices, copper. selenium, silver, and microbial pathogens; while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma’s and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals. These new and emerging concepts of applications of metals in medicine, their crucial role in management of microbial resistance, and their use in the treatment of various chronic diseases is essential information for toxicologists, and clinical and biomedical researchers.

Author: Inamuddin
Publisher: John Wiley & Sons
ISBN: 1119654882
Category : Technology & Engineering
Languages : en
Pages : 240

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Book Description
Alloy Materials and Their Allied Applications provides an in-depth overview of alloy materials and applications. The 11 chapters focus on the fabrication methods and design of corrosion-resistant, magnetic, biodegradable, and shape memory alloys. The industrial applications in the allied areas, such as biomedical, dental implants, abrasive finishing, surface treatments, photocatalysis, water treatment, and batteries, are discussed in detail. This book will help readers solve fundamental and applied problems faced in the field of allied alloys applications.

Author: Mike Driver
Publisher: Elsevier
ISBN: 0857093673
Category : Science
Languages : en
Pages : 381

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Book Description
The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications. The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices. With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings. Provides an extensive review of coating types and surface modifications for biomedical applications Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices

Author: Valentina Grumezescu
Publisher: Elsevier
ISBN: 0128168757
Category : Medical
Languages : en
Pages : 596

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Book Description
Materials for Biomedical Engineering: Thermoset and Thermoplastic Polymers presents the newest and most interesting approaches to intelligent polymer engineering in both current and future progress in biomedical sciences. Particular emphasis is placed on the properties needed for each selected polymer and how to increase their biomedical potential in varying applications, such as drug delivery and tissue engineering. These materials are intended for use in diagnoses, therapy and prophylaxis, but are also relatable to other biomedical related applications, such as sensors. Recent developments and future perspectives regarding their use in biomedicine are discussed in detail, making this book an ideal source on the topic. Highlights the most well-known applications of thermoset and thermoplastic polymers in biological and biomedical engineering Presents novel opportunities and ideas for developing or improving technologies in materials for companies, those in biomedical industries, and others Features at least 50% of references from the last 2-3 years

Author: Noam Eliaz
Publisher: Springer Science & Business Media
ISBN: 1461439426
Category : Technology & Engineering
Languages : en
Pages : 521

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Book Description
This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.

Author: David Hernandez Escobar
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 308

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Book Description
Absorbable metals have the potential to serve as the next generation of temporary medical implants by safely dissolving in the human body upon vascular tissue healing and bone regeneration. Their incorporation in the market could greatly reduce the need and risks associated with additional surgeries and other complications often related to permanent devices. Despite the extensive research on magnesium (Mg) and iron (Fe) based alloys over the last two decades, they have not exhibited an optimal combination of mechanical properties, biocompatibility, and controlled degradation rate for absorbable implant applications. Zinc (Zn) and Zn-based alloys have recently emerged as an alternative, as they have demonstrated an attractive combination of in vivo biocompatibility and degradation behavior. However, their mechanical properties are generally insufficient for load-bearing implant applications.In this dissertation, Zn-xMg (x = 3, 10, 30 wt.%) hybrid samples were synthesized for the first time using high-pressure torsion (HPT) to mechanically bond pure Zn and Mg disks. These samples were characterized to investigate their processing-microstructure-property relationships. The effects of HPT on the microstructural and hardness evolution were systematically studied in all the materials, with special emphasis on the regions of highest plastic deformation. The effects of post-deformation annealing (PDA) on the Zn-3Mg hybrid were also investigated. Also, an as-homogenized Zn-3Mg (wt.%) alloy was HPT-processed and subjected to PDA, and the microstructure and hardness evolution was compared with that of the Zn-3Mg hybrid. In addition, four different biodegradable coatings (based on zinc phosphate (ZnP), collagen (Col), and Ag-doped bioactive glass nanoparticles (AgBGN)) were synthesized by chemical conversion, spin-coating, or a combination of both, on the as-homogenized Zn-3Mg alloy substrates. The effects of the coatings on the in vitro degradation behavior, cytocompatibility, and antibacterial activity were evaluated.A significant microstructural refinement was obtained after HPT processing for 30 turns, reaching equiaxed grains of ~ 200 nm in both the Zn-3Mg hybrid and alloy. Unlike in the alloy, HPT induced the nucleation of Mg2Zn11 and MgZn2 intermetallic compounds, as well as the formation of supersaturated solid solutions in the hybrid, both of which led to maximum hardness values in the range of ~ 220-230 HV. PDA resulted in both an increased hardness (up to ~ 250 HV) and strain rate sensitivity. A plastic deformation model is proposed to explain the strain-hardening behavior of the hybrid after PDA, which suggested an enhanced strength-ductility relationship. This was consistent with the strain rate sensitivity results from nanoindentation.In vitro degradation of ZnP coated samples for 21 days immersion showed a controlled weight loss over time associated with a decreased corrosion rate, while maintaining a physiological pH range of 7.5-7.6. The uncoated, ZnP coated, and Col-AgBGN coated sample extracts led to higher cell viability over 6 days culture, which generally increased with extract concentration. In addition, the Col-AgBGN coated samples led to ~ 31 % bacterial viability, compared to the ~ 65-75 % of the other samples, hence, indicating a strong antibacterial effect.Overall, the insights gained from this dissertation enabled a better understanding of the composition-processing-microstructure-property relationships of the Zn-Mg system and served as a roadmap for the design of hybrid materials with enhanced mechanical properties. Moreover, the synthesis of biodegradable coatings has potential to tailor the Zn-Mg materials for specific biomedical implant applications.

Author: Bingyun Li
Publisher: Springer
ISBN: 3319736647
Category : Medical
Languages : en
Pages : 614

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Book Description
This book covers the latest advances, applications, and challenges in orthopedic biomaterials. Topics covered include materials for orthopedic applications, including nanomaterials, biomimetic materials, calcium phosphates, polymers, biodegradable metals, bone grafts/implants, and biomaterial-mediated drug delivery. Absorbable orthopedic biomaterials and challenges related to orthopedic biomaterials are covered in detail. This is an ideal book for graduate and undergraduate students, researchers, and professionals working with orthopedic biomaterials and tissue engineering. This book also: Describes biodegradable metals for orthopedic applications, such as Zn-based medical implants Thoroughly covers various materials for orthopedic applications, including absorbable orthopedic biomaterials with a focus on polymers Details the state-of-the-art research on orthopedic nanomaterials and nanotechnology