Author: Catherine Sautes-FridmanPublisher: Frontiers Media SA
ISBN: 283252544X
Category : Medical
Languages : en
Pages : 148
Book Description
A year in review: Discussions in cancer immunity and immunotherapy
Author: Catherine Sautes-FridmanPublisher: Frontiers Media SA
ISBN: 283252544X
Category : Medical
Languages : en
Pages : 148
Book Description
Cancer Immunology and Immunotherapy
Author: Mansoor M. AmijiPublisher: Elsevier
ISBN: 0128233974
Category : Business & Economics
Languages : en
Pages : 548
Book Description
Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO
A Year in Review: Discussions in Immunological Memory
Author: Scott N. MuellerPublisher: Frontiers Media SA
ISBN: 2832507816
Category : Medical
Languages : en
Pages : 138
Book Description
Cancer Immunotherapy Principles and Practice
Author: Lisa H. ButterfieldPublisher:
ISBN: 9781620700976
Category : Cancer
Languages : en
Pages : 0
Book Description
Part 1: Intratumoral Signatures Associated With Immune Responsiveness
Immunotherapy of Hepatocellular Carcinoma
Author: Tim F. GretenPublisher: Springer
ISBN: 9783319879116
Category : Medical
Languages : en
Pages : 0
Book Description
In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
Anti-tumor Activity of Cytotoxic Immune Cells: Basic Research and Clinical Perspectives
Author: Malgorzata Firczuk Publisher: Frontiers Media SA
ISBN: 283254942X
Category : Medical
Languages : en
Pages : 121
Book Description
Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells are powerful effectors of antitumor immunity. CTL recognize tumor antigens presented by human leukocyte antigen (HLA) molecules with antigen-specific T cell receptors (TCR) and are the key effector cells of the adaptive immune response. In contrast, NK cells lack antigen-specific receptors and are regulated by the balance of signals from activating and inhibitory receptors. These two types of cells cooperate and complement each other in eliciting host immune response to cancer and mediating immune surveillance. Moreover, these cells play a crucial role in antitumor immunotherapy, including monoclonal antibodies (mAbs), bispecific T cell engagers (BiTe), as well as adoptive transfer of chimeric antigen receptor (CAR)-modified cytotoxic cells.
Tumor Microenvironment, Inflammation, and Resistance to Immunotherapies
Author: Apostolos ZaravinosPublisher: Frontiers Media SA
ISBN: 2832527124
Category : Medical
Languages : en
Pages : 218
Book Description
Tumor-Associated Antigens and Their Autoantibodies: From Discovering to Clinical Utilization
Author: Xiangqian GuoPublisher: Frontiers Media SA
ISBN: 2889767973
Category : Medical
Languages : en
Pages : 192
Book Description
NK cell modifications to advance their anti-tumor activities
Author: Ye LiPublisher: Frontiers Media SA
ISBN: 2832532845
Category : Medical
Languages : en
Pages : 198
Book Description
Immune Cell Lineage Reprogramming in Cancer
Author: Jianmei Wu LeavenworthPublisher: Frontiers Media SA
ISBN: 2889744736
Category : Medical
Languages : en
Pages : 244
Book Description
Topic Editor Dr. Lewis Shi received financial support from Varian Medical System, Inc. The other Topic Editors declare no competing interests with regard to the Research Topic subject.