A Survey of Compounds from the Antiradiation Drug Development Program of the U.S. Army Medical Research and Development Command PDF Download

Author: Thomas Richard Sweeney
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 870

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Author: Ching Kuang Chow
Publisher: CRC Press
ISBN: 1000697312
Category : Medical
Languages : en
Pages : 375

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First Published in 1988, this three-volume set offers a full insight into the immune systems and its response to antioxidants. Carefully compiled and filled with diagrams, references and information this set is recommended for students of immunology and other professionals in their respective fields.

Author: Michael R. Quastel
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 268

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Author: Edward A. Bump
Publisher: CRC Press
ISBN: 1000103048
Category : Law
Languages : en
Pages : 446

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It is essential to minimize damage to normal tissues during radiation therapy and many strategies have been employed in finding the best methods for radioprotection. This book integrates chemical, biological, and clinical perspectives on these strategies and developments, providing a comprehensive treatise. It emphasizes new concepts in radioprotection, aiming to inspire further basic science and clinical progress in radioprotector research. Radioprotectors: Chemical, Biological, and Clinical Perspectives includes the following topics: Early research on radioprotectors WR-2721, an aminothiol prodrug, as a radioprotector New results with naturally occurring thiols Nitroxides as effective radioprotectors in vitro and in vivo Radioprotection observed with radical scavengers or antioxidants Bone marrow radioprotection with cytokines and biological modifiers Multiple mechanisms of altering radiation response by eicosanoids Vascular response to radiation and the importance of vascular damage to normal tissue Modifiers of radiation-induced apoptosis Survey of clinical trials with radioprotectors Radiation biologists and oncologists, cancer researchers, and toxicologists will benefit from the findings discussed and strategies for future research.

Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 664

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Author: Sang Hyun Cho
Publisher: Taylor & Francis
ISBN: 1439878765
Category : Medical
Languages : en
Pages : 281

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Rapid advances in nanotechnology have enabled the fabrication of nanoparticles from various materials with different shapes, sizes, and properties, and efforts are ongoing to exploit these materials for practical clinical applications. Nanotechnology is particularly relevant in the field of oncology, as the leaky and chaotic vasculature of tumors-a

Author: Jules E. Harris
Publisher: CRC Press
ISBN: 9780849369032
Category : Medical
Languages : en
Pages : 266

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This book provides an updated overview of eicosanoid metabolism. It also presents a timely discussion of eicosanoid metabolism in the process of tumor cell metastasis, in chemoprotection and radioprotection associated with cancer therapy, and in cell differentiation. The book focuses on the role of eicosanoids in the immunology of malignant disease. This includes how various immune cell populations in cancer are affected by the secretion and action of various eicosanoids and metabolites of eicosanoids and how these processes may be affected by various pharmacological manipulations and interventions to augment anti-tumor immunity. Head and neck cancer is covered in great detail to illustrate a cancer in humans where these considerations are particularly relevant. This important volume demonstrates that the principal factor in cancer patient immunologic deficiency is related to excess secretion by monocytes of prostaglandins.

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 9815040774
Category : Medical
Languages : en
Pages : 248

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Frontiers in Natural Product Chemistry is a book series devoted to important advances in natural product chemistry. The series features volumes that cover all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. Volume 10 of the series brings together 5 reviews on a variety of bioactive compounds. An overview of cistus species growing in Sardinia: a source of bioactive compounds Roles of natural abscisic acids in fruits during fruit development and under environmental stress Progress in the research of naturally occurring biflavonoids: a look through Plant metabolites for protecting human cells against radiation-associated damage: an integrative review Chemical perspective and drawbacks in flavonoid estimation assays

Author: Christa Baumstark-Khan
Publisher: Springer Science & Business Media
ISBN: 9401145857
Category : Technology & Engineering
Languages : en
Pages : 544

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Human health as well as aquatic and terrestrial ecosystems are threatened from increa sing levels of environmental radiation of various sources, many of them of anthropoge nic causality: large areas of the former Soviet Union suffer from radioactive pollution, in particular after the Chemobyl accident; the increase in the incidence of UVB radiati on at the Earth's surface as a result of a progressive depletion of stratospheric ozone is a global problem that requires international concerted actions; in areas of former uranium mining the natural radiation level is substantially increased due to elevated radon levels; a growing portion of the population involved in air traffic is exposed to increased levels of natural radiation; and with the International Space Station an increasing number of astronauts will be exposed to the complex field of cosmic radiation. To estimate the corresponding risks, a better knowledge of the underlying radiobiological mechanisms at the molecular, cellular and system level is required. This book is the result of a multidisciplinary effort to discuss the current state of knowledge of the fundamental processes that result from interactions of environmental radiation -ionizing as well as UV radiation -with living matter and the existing radiati on protection concepts, and then to define future research work needed as fundamental information for the assessment of risks from increased levels of environmental radiation to human health and ecosystem balance. It comprises the key lectures and statements presented at the NATO Advanced Research Workshop.

Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 1114

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