Author: Sam Stuart Publisher: Elsevier ISBN: 1483181189 Category : Medical Languages : en Pages : 45
Book Description
A Review of the Radiosensitivity of the Tissues in Bone is a report prepared by the Task Group for the International Commission on Radiological Protection Committees 1 and 2. The book reviews a biological indicator of the maximum permissible radiation dose. Data shows that an induction of malignant change should be considered as the limiting factor in maximum permissible levels for the bone. The risk of carcinogenesis in cells is connected with the proliferative potential of the cells. These cells are on bone marrow surfaces, in hematopoietic marrow, and in certain epithelial cells close to bone surfaces. The text also reviews the changes in the patterns of distribution resulting from growth and remodeling of bone. The book examines the effect of distribution of alkaline earth, of plutonium, of thorium, of americium, and of phosphorus in bone growth. The book also evaluates the comparative tumorigenic effects of external and internal irradiation of bone and the factors to be considered in determining the dose limitation from bone-seeking radionuclides. This book can prove beneficial to researchers and practitioners in the fields of radiology, internal medicine, or oncology.
Author: Simon S. Lo Publisher: Springer Science & Business Media ISBN: 364225604X Category : Medical Languages : en Pages : 433
Book Description
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Author: National Research Council Publisher: National Academies Press ISBN: 0309037891 Category : Science Languages : en Pages : 623
Book Description
This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Author: ICRP, Publisher: SAGE Publications Limited ISBN: 9781473952065 Category : Science Languages : en Pages : 0
Book Description
This report provides a review of stem cells/progenitor cells and their responses to ionising radiation in relation to issues relevant to stochastic effects of radiation which form a major part of the ICRP system of radiological protection. Current information on stem cell characteristics, maintenance and renewal, evolution with age, location in stem cell “niches”, radiosensitivity to acute and protracted exposures, is presented in a series of substantial reviews as Annexes concerning haematopoietic tissue, mammary gland, thyroid, digestive tract, lung, skin and bone. This foundation of knowledge of stem cells is used in the main text of the report to provide a biological insight to issues such as the linear-no-threshold (LNT) model, cancer risk among tissues, dose-rate effects and changes in the risk of radiation carcinogenesis by age at exposure and attained age.
Author: Mammen Chandy Publisher: Springer ISBN: 9783030363574 Category : Medical Languages : en Pages : 0
Book Description
Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.
Author: Dennis C. Shrieve Publisher: Lippincott Williams & Wilkins ISBN: 1605470112 Category : Medical Languages : en Pages : 212
Book Description
Human Radiation Injury is a concise but thorough presentation of known toxicities of radiation exposure in humans. This unique text is the only single reference available that studies the risks to humans from medical, environmental, and accidental or terrorist-related exposure to radiation. The chapters cover modern understanding of the molecular and cellular events involved in radiation injury, the known dose-effect relationships for human organ systems, and a full discussion of normal tissue toxicity related to therapeutic radiation. Recommended guidelines are outlined and the best available treatments following injury are also detailed. A companion website offers the fully searchable text and an image bank.
Author: Sam Stuart
Author: Simon S. Lo
Author: National Research Council
Author: ICRP,
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Author: Mammen Chandy
Author: Dennis C. Shrieve
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Author: Philip Rubin
Author: J. W. Stather