Author: Theodore S. HigsonPublisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 160
Book Description
A Cellular and Molecular Genetic Analysis of Star and Asteroid Mutations which Disrupt Eye Development in Drosophila Melanogaster
Author: Theodore S. HigsonPublisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 160
Book Description
A Genetic Analysis of Retinal Development in Drosophila Melanogaster
Author: David Landreth Van VactorPublisher:
ISBN:
Category :
Languages : en
Pages : 240
Book Description
A Molecular and Genetic Analysis of the Developing Visual System in Drosophila Melanogaster
Author: Allen James Ebens (Jr.)Publisher:
ISBN:
Category :
Languages : en
Pages : 260
Book Description
Analysis of Star and Asteroid Mutations of Drosophila Melanogaster
Author: Stacey A. SedoreA Phenotypic, Genetic and Molecular Analysis of the Developing Drosophila Melanogaster Visual System
Author: Benjamin N. R. CheyettePublisher:
ISBN:
Category :
Languages : en
Pages : 200
Book Description
A Characterization of the Star Gene and Its Role in Epidermal Growth Factor Receptor Signaling During Drosophila Development
Author: Amanda Tracey PickupPublisher:
ISBN:
Category :
Languages : en
Pages : 236
Book Description
A Genetic Analysis of the Development of the Visual System in Drosophila Melanogaster
Author: Peter John HarteA Genetic and Molecular Analysis of Drosophila Melanogaster Visual System Development
Author: Birong HuThe Roles of Drosophila Genes TF11A-S and F125 During Compound Eye Development
Author: Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
The Drosophila compound eye represents an experimental system in which developmental decisions can be observed at a single-cell resolution. During larval development undifferentiated cells are sequentially recruited to form the individual subunits of the eye via cell-cell interactions which require Ras pathway activity.In this thesis I present the characterisation of two genes which play a part in eye development which were identified as part of the analysis of an enhancer detector P- element insertion. These are the small subunit of the basal transcription factor IIA (dTFIIA-S) and F125.dTFIIA-S was cloned and is transiently expressed in photoreceptor cells during their determination. Mutations generated in this locus are homozygous cellular lethal. However, a putative hypomorphic allele disrupts ommatidial assembly and eye development. In addition, these mutations act as dominant second-site suppressers of the rough eye phenotype caused by ectopic activation of the Ras pathway in eye development. The interactions between TFIIA and transcription factors activated by Ras in vivo can thus be genetically dissected and appear to support previous in vitro studies.FI25 was isolated and sequenced and encodes a novel protein. It is expressed during embryonic and eye development. A P-element allele of FI25 was obtained and represents a hypomorphic mutation in the locus which is characterised by a failure of rhabdomere development. Additional alleles of FI25 were generated by remobilisation of the mutagenic P-element insertion and are currently being investigated.
Author: