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Molecular Biology of the Toxic Response

Molecular Biology of the Toxic Response PDF Author: Alvaro Puga
Publisher: CRC Press
ISBN: 9781439805978
Category : Medical
Languages : en
Pages : 604

Book Description
Encouraging the incorporation of molecular biology techniques into the experimental approach to various toxicological problems, the format of the book is two-staged. Each chapter first introduces how various molecular techniques can be successfully applied to solving a specific toxicology question and proceeds to describe the techniques themselves. Also included is a discussion of the benefits and limitations of these techniques . This book will prove of value to practising researchers, but also to graduate students dealing with conceptual issues relating to molecular toxicology.

Veterans and Agent Orange

Veterans and Agent Orange PDF Author: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides
Publisher: National Academies Press
ISBN: 9780309075299
Category : Medical
Languages : en
Pages : 791

Book Description
Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.

Molecular Biology of the Toxic Response

Molecular Biology of the Toxic Response PDF Author: Alvaro Puga
Publisher: CRC Press
ISBN: 9781439805978
Category : Medical
Languages : en
Pages : 604

Book Description
Encouraging the incorporation of molecular biology techniques into the experimental approach to various toxicological problems, the format of the book is two-staged. Each chapter first introduces how various molecular techniques can be successfully applied to solving a specific toxicology question and proceeds to describe the techniques themselves. Also included is a discussion of the benefits and limitations of these techniques . This book will prove of value to practising researchers, but also to graduate students dealing with conceptual issues relating to molecular toxicology.

Cytochrome P450

Cytochrome P450 PDF Author: John B. Schenkman
Publisher: Springer Science & Business Media
ISBN: 3642777635
Category : Medical
Languages : en
Pages : 740

Book Description
The most complete and up-to-date survey of this important superfamily of enzymes, including the first ever coverage of the forms involved in steroid hormone biosynthesis. The components of the enzyme system, the reaction mechanisms involved, and the evolution and nomenclature are analyzed, as is the hepatic microsomal enzyme in a large number of species, illustrating the very wide implications for life processes.

DNA-protein Interactions of the Dioxin Receptor Complex

DNA-protein Interactions of the Dioxin Receptor Complex PDF Author: Steven Bacsi
Publisher:
ISBN:
Category :
Languages : en
Pages : 416

Book Description


The Chemical Scythe

The Chemical Scythe PDF Author: Alastair Hay
Publisher: Springer Science & Business Media
ISBN: 1489903399
Category : Medical
Languages : en
Pages : 267

Book Description
The Chemical Scythe is the first book in a projected series to be published by Plenum Press in association with the International Disaster Institute. The aim of the series, Disaster Research in Practice, is to provide scientific and readable accounts on the most urgent areas of disaster research. It is fitting, therefore, that Dr. Hay's investigation into the nature and effects of dioxins heralds the new series. The problem of chemical hazards is one that we will have to learn to live with in future decades. Dr. Hay's book is an authoritative account of the chemistry and proven and potential effects of dioxins, and of the impli cations for safety planning. He concludes with a cautious, yet optimistic note-that indeed we can learn to live with such hazards, providing that we are prepared to understand and plan for the unexpected. The accident at Seveso in 1976 alerted the world to an imperfectly un derstood but immensely alarming environmental hazard. Public debate and argument as to the implications of dioxins and, indeed, the use of herbicides as aggressive weapons in Vietnam, rage on. And yet it is only through the painstaking research exemplified in this book that it will eventually be pos sible to promote the vital accountability on the part of industrialists and governments.

Annual Review of Pharmacology and Toxicology

Annual Review of Pharmacology and Toxicology PDF Author: Arthur K. Cho
Publisher: Annual Reviews
ISBN: 9780824304393
Category : Medical
Languages : en
Pages : 488

Book Description
Papers detail research and findings surrounding advances in the field. Topics include regulation and role in drug metabolism of cytochrome P- 450 3A4, molecular and pharmacologic regulation of the pineal gland, regulation of gene expression by reactive oxygen, cytotoxicity of short-chain alcohols, glial cells in neurotoxicity development, and regulation and inhibition of phospholipase A2. Other subjects include inhibition of nitric oxide synthase as a potential therapeutic target, genetic regulation of glutamate receptor ion channels, and teratology of retinoids. Annotation copyrighted by Book News, Inc., Portland, OR

Toxicology in Transition

Toxicology in Transition PDF Author: Gisela H. Degen
Publisher: Springer
ISBN: 9783642794537
Category : Medical
Languages : en
Pages : 0

Book Description
The volume contains the main papers presented at the 1994 EUROTOX Congress, Basel, Switzerland, August 21-24, 1994. Toxicology has become a less descriptive science because more importance has been placed on the mechanisms underlying toxic effects. This is reflected in symposia and workshops devoted to species differences in organ toxicity, receptor-mediated toxicity and stereochemical effects of xenobiotics. Recent progress in the fields of immunotoxicology, ecotoxicology, and neurotoxicology is highlighted and documented together with the present discussion on harmonized regulatory guidelines.

Characterization of the Ahr Locus and Generation of a Null Allele

Characterization of the Ahr Locus and Generation of a Null Allele PDF Author: Jennifer Virginia Schmidt
Publisher:
ISBN:
Category :
Languages : en
Pages : 404

Book Description


Canadian Arctic Contaminants Assessment Report

Canadian Arctic Contaminants Assessment Report PDF Author: Northern Contaminants Program (Canada)
Publisher: Canadian Museum of Civilization/Musee Canadien Des Civilisations
ISBN:
Category : Nature
Languages : en
Pages : 154

Book Description


Developmental Regulation of Rabbit Cyp1A1 and Cyp1A2

Developmental Regulation of Rabbit Cyp1A1 and Cyp1A2 PDF Author: David Kelly Strom
Publisher:
ISBN:
Category :
Languages : en
Pages : 254

Book Description