Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240000194
Category : Medical
Languages : en
Pages : 48
Book Description
2019 Antibacterial agents in clinical development
Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240000194
Category : Medical
Languages : en
Pages : 48
Book Description
2019 ANTIBACTERIAL AGENTS IN CLINICAL DEVELOPMENT: an Analysis of the Antibacterial Clinical Development Pipeline
Author: Antibacterial Agents in Clinical Development
Author: Publisher:
ISBN:
Category : Antibacterial agents
Languages : en
Pages : 45
Book Description
"A new WHO report shows a serious lack of new antibiotics under development to combat the growing threat of antimicrobial resistance. The report found very few potential treatment options for those antibiotic-resistant infections identified by WHO as posing the greatest threat to health, including drug-resistant tuberculosis which kills around 250,000 people each year."--
2020 Antibacterial agents in clinical and preclinical development
Author: Publisher: World Health Organization
ISBN: 9240021302
Category : Business & Economics
Languages : en
Pages : 76
Book Description
This report is the World Health Organization’s (WHO) fourth annual review of the clinical antibacterial pipeline, and the second review of the preclinical antibacterial pipeline. The WHO’s annual antibacterial pipeline report reviews antibiotics that are in the clinical stages of development as well as those in early development to assess the progress and gaps in relation to urgent threat of drug-resistance.The report evaluates the potential of these antibacterial candidates in development to address the most threatening drug-resistant bacteria as outlined in the WHO Bacterial Priority Pathogens List (WHO PPL). This report covers direct-acting small molecules and biological agents that are in development worldwide. In this fourth edition, the report includes for the first time a comprehensive overview of non-traditional antibacterial medicines. This report is part of the WHO’s efforts in global research and development (R&D) priority setting to contain antimicrobial resistance. All the data contained in this report can be downloaded from the WHO Global Observatory on Health R&D.
2021 Antibacterial agents in clinical and preclinical development
Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240047654
Category : Business & Economics
Languages : en
Pages : 104
Book Description
Antibacterial pipeline trends and recommendations to enhance research and development
Author: World Health OrganizationPublisher: World Health Organization
ISBN: 9240097732
Category : Medical
Languages : en
Pages : 16
Book Description
The World Health Organization (WHO) policy brief, "Antibacterial pipeline trends and recommendations to enhance research and development" provides recommendations to strengthen R&D for antibacterials based on current trends in the antibacterial pipeline, as part of a comprehensive effort to address persistent global health challenge posed by antimicrobial resistance (AMR). This WHO policy brief is based on the latest WHO pipeline report “2023 Antibacterial agents in clinical and preclinical development: an overview and analysis” (IRIS link) and is intended to serve as a tool for drug developers, policymakers and funders of research and development (R&D) in AMR and basic AMR research. The goal of this WHO policy brief is to guide the implementation of strategies to respond to persistent R&D challenges and strengthen the antibacterial pipeline. It highlights the continued urgent need for innovative drugs to combat drug-resistant infections, particularly against priority pathogens identified in the 2024 WHO Bacterial Priority Pathogen List (IRIS link) and other crucial gaps in the pipeline including drugs to address serious bacterial infections in the populations most affected, such as vulnerable patient populations. The WHO policy brief emphasizes global coordination and collaboration to advance R&D for antibacterial agents.
Antibiotic Discovery and Development
Author: Thomas J. DoughertyPublisher: Springer Science & Business Media
ISBN: 1461414008
Category : Medical
Languages : en
Pages : 1119
Book Description
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
2021 ANTIBACTERIAL AGENTS IN CLINICAL AND PRECLINICAL DEVELOPMENT: an Overview and Analysis
Author: world health organizationPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Update of Antibacterial Agents in Clinical Development
Author: world health organizationPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Author: