Author: Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Reversal of Multidrug Resistance in Cancer
Author: 1st International Conference on Reversal of Multidrug Resistance in Cancer, St Gallen, Switzerland, 1-3 September 1994
Author: International Conference on Reversal of Multidrug Resistance in Cancer (1, 1994, Sankt Gallen)Publisher:
ISBN:
Category :
Languages : en
Pages : 79
Book Description
1st International Conference on Reversal of Multidrug Resistance in Cancer
Author: Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 79
Book Description
Dexverapamil
Author: Publisher:
ISBN:
Category : Drug resistance in cancer cells
Languages : en
Pages : 0
Book Description
Dexverapamil: a clinical approach to circumvention of multidrug resistance
Author: International Conference on Reversal of Multidrug Resistance in CancerPublisher:
ISBN:
Category :
Languages : de
Pages : 29
Book Description
Reversal of Multidrug Resistance in Cancer
Author: John A. KellenPublisher: CRC Press
ISBN: 9780849347443
Category : Medical
Languages : en
Pages : 164
Book Description
This critical, state-of-the-art review brings together the scattered and often controversial information on multidrug resistance reversal. Leading scientists in the field cover P-glycoprotein, the genetics of resistance, and its reversal by drugs. Resistance modifiers and modulators are tabulated and critically evaluated. Reversal of Multidrug Resistance in Cancer is important reading for oncologists, cancer chemotherapists, and other cancer researchers.
Journal of the National Cancer Institute
Author: Multi-Drug Resistance in Cancer
Author: Jun ZhouPublisher: Humana Press
ISBN: 9781617796647
Category : Medical
Languages : en
Pages : 492
Book Description
Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .
Author: 
Author: